Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2011 1
2012 1
2014 2
2015 2
2017 1
2018 2
2019 1
2020 1
2021 4
2022 1
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

15 results

Results by year

Filters applied: . Clear all
Page 1
Did you mean POU4F1 and nerve regeneration (7 results)?
Progressive Retinal and Optic Nerve Damage in a Mouse Model of Spontaneous Opticospinal Encephalomyelitis.
Petrikowski L, Reinehr S, Haupeltshofer S, Deppe L, Graz F, Kleiter I, Dick HB, Gold R, Faissner S, Joachim SC. Petrikowski L, et al. Front Immunol. 2022 Jan 24;12:759389. doi: 10.3389/fimmu.2021.759389. eCollection 2021. Front Immunol. 2022. PMID: 35140707 Free PMC article.
Here, we investigated inflammation and degeneration of the visual system in a spontaneous encephalomyelitis animal model. ...In summary, we describe characteristics of inflammation and degeneration of the visual system in a spontaneous encephalomyelitis model, chara …
Here, we investigated inflammation and degeneration of the visual system in a spontaneous encephalomyelitis animal model. ...In summa …
Nerve fibre layer degeneration and retinal ganglion cell loss long term after optic nerve crush or transection in adult mice.
Sánchez-Migallón MC, Valiente-Soriano FJ, Salinas-Navarro M, Nadal-Nicolás FM, Jiménez-López M, Vidal-Sanz M, Agudo-Barriuso M. Sánchez-Migallón MC, et al. Exp Eye Res. 2018 May;170:40-50. doi: 10.1016/j.exer.2018.02.010. Epub 2018 Feb 13. Exp Eye Res. 2018. PMID: 29452106 Free article.
We have investigated the long term effects of two different models of unilateral optic nerve (ON) lesion on retinal ganglion cells (RGCs) and their axons, in the injured and contralateral retinas of adult albino mice. ...
We have investigated the long term effects of two different models of unilateral optic nerve (ON) lesion on retinal ganglion cells (R …
Molecular, anatomical and functional changes in the retinal ganglion cells after optic nerve crush in mice.
Yukita M, Machida S, Nishiguchi KM, Tsuda S, Yokoyama Y, Yasuda M, Maruyama K, Nakazawa T. Yukita M, et al. Doc Ophthalmol. 2015 Apr;130(2):149-56. doi: 10.1007/s10633-014-9478-2. Epub 2015 Jan 6. Doc Ophthalmol. 2015. PMID: 25560383
PURPOSE: Optic nerve crush (ONC) and subsequent axonal damage can be used in rodents to study the mechanism of retinal ganglion cell (RGC) degeneration. ...The pSTR, a- and b-wave amplitudes were measured. Inner retinal thickness around the optic nerve head w …
PURPOSE: Optic nerve crush (ONC) and subsequent axonal damage can be used in rodents to study the mechanism of retinal ganglion cell …
HSP27 induced glaucomatous damage in mice of young and advanced age.
Erb C, Reinehr S, Theiss C, Dick HB, Joachim SC. Erb C, et al. Front Cell Neurosci. 2023 Sep 7;17:1257297. doi: 10.3389/fncel.2023.1257297. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37744880 Free PMC article.
Comparing aged and young HSP27 mice, no differences in Rbpms and Pou4f1 (RGCs) expression was detected, while the Tubb3 expression (neuronal cells) was significantly upregulated in aged HSP27 animals. ...The aged HSP27 group displayed an upregulated Hspb2 expression compar …
Comparing aged and young HSP27 mice, no differences in Rbpms and Pou4f1 (RGCs) expression was detected, while the Tubb3 expression (n …
Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro.
Zhang L, Li X. Zhang L, et al. Exp Cell Res. 2020 Nov 1;396(1):112159. doi: 10.1016/j.yexcr.2020.112159. Epub 2020 Jul 9. Exp Cell Res. 2020. PMID: 32652081
Traumatic optic neuropathy is a common clinical problem. Damage to the optic nerve leads to shear stress and triggers secondary swelling within the optic canal. The study aims to explore the role of the inflammatory response following optic nerve injury (ONI) in tol …
Traumatic optic neuropathy is a common clinical problem. Damage to the optic nerve leads to shear stress and triggers secondary swell …
Adult mice transplanted with embryonic retinal progenitor cells: new approach for repairing damaged optic nerves.
Cho JH, Mao CA, Klein WH. Cho JH, et al. Mol Vis. 2012;18:2658-72. Epub 2012 Nov 12. Mol Vis. 2012. PMID: 23170059 Free PMC article.
PURPOSE: Retinal ganglion cell (RGC) death and optic nerve degeneration are complex processes whose underlying molecular mechanisms are only vaguely understood. Treatments commonly used for optic nerve degeneration have little long-term value and only …
PURPOSE: Retinal ganglion cell (RGC) death and optic nerve degeneration are complex processes whose underlying molecular mecha …
O-GlcNAc Transferase Is Essential for Sensory Neuron Survival and Maintenance.
Su C, Schwarz TL. Su C, et al. J Neurosci. 2017 Feb 22;37(8):2125-2136. doi: 10.1523/JNEUROSCI.3384-16.2017. Epub 2017 Jan 23. J Neurosci. 2017. PMID: 28115479 Free PMC article.
The effects on neuronal health in vivo are not solely due to disruption of developmental processes, because inducing OGT knock-out in the sensory neurons of adult mice results in a similar decrease in nerve fiber endings and cell bodies. Significant nerve-ending los …
The effects on neuronal health in vivo are not solely due to disruption of developmental processes, because inducing OGT knock-out in the se …
Microglia mediate non-cell-autonomous cell death of retinal ganglion cells.
Takeda A, Shinozaki Y, Kashiwagi K, Ohno N, Eto K, Wake H, Nabekura J, Koizumi S. Takeda A, et al. Glia. 2018 Nov;66(11):2366-2384. doi: 10.1002/glia.23475. Epub 2018 Oct 29. Glia. 2018. PMID: 30375063
Taken together, our data demonstrate that a phenotypic change of microglia into a neurotoxic one is a critical event for the NMDA-induced degeneration of RGCs, suggesting an importance of non-cell-autonomous mechanism in the retinal neuronal excitotoxicity....
Taken together, our data demonstrate that a phenotypic change of microglia into a neurotoxic one is a critical event for the NMDA-induced …
Rescue of retinal function by BDNF in a mouse model of glaucoma.
Domenici L, Origlia N, Falsini B, Cerri E, Barloscio D, Fabiani C, Sansò M, Giovannini L. Domenici L, et al. PLoS One. 2014 Dec 23;9(12):e115579. doi: 10.1371/journal.pone.0115579. eCollection 2014. PLoS One. 2014. PMID: 25536045 Free PMC article.
Vision loss in glaucoma is caused by progressive dysfunction of retinal ganglion cells (RGCs) and optic nerve atrophy. Here, we investigated the effectiveness of BDNF treatment to preserve vision in a glaucoma experimental model. ...
Vision loss in glaucoma is caused by progressive dysfunction of retinal ganglion cells (RGCs) and optic nerve atrophy. Here, we inves …
15 results